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Metoprolol
Clinical data
Pronunciation/ m ɛ ˈ t oʊ p r oʊ l ɑː l /, / m ɛ t oʊ ˈ p r oʊ l ɑː l /
Trade namesLopressor, Metolar XR, others
AHFS/Drugs.comMonograph
MedlinePlusa682864
License dataUS   FDA: Metoprolol
Pregnancy categoryAU: C US: C (Risk not ruled out)
Routes of administrationBy mouth, IV
Drug classBeta blocker
ATC codeC07AB02 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability50% (single dose) [1] 70% (repeated administration) [2]
Protein binding12%
MetabolismLiver via CYP2D6, CYP3A4
Elimination half-life3–7 hours
ExcretionKidney

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-56 Epub 2007 Jun 18 PubMed Google Scholar 73. Australia/New Zealand Heart Failure Research Collaborative GroupRandomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease.ollow your diet, medication, and exercise routines very closely.

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