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Simvastatin
Clinical data
Pronunciation/ ˈ s ɪ m v ə s t æ t ɪ n /
Trade namesZocor, other
AHFS/Drugs.comMonograph
MedlinePlusa692030
License dataEU  EMA:  by INN, US   FDA: Simvastatin
Pregnancy categoryAU: D US: X (Contraindicated)
Routes of administrationby mouth
ATC codeC10AA01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: P (Pharmacy medicines) when ≤10 mg/day, POM when >10 mg/day., US: ℞-only
Pharmacokinetic data
Bioavailability5%
Protein binding95%
MetabolismHepatic (CYP3A4)
Elimination half-life2 hours for simvastatin and 1.9 hours for simvastatin acid
ExcretionRenal 13%, faecal 60%

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Simvastatin instruction
Drug name Simvastatin
Simvastatin all alternative namesactalipid, docsimvasta, doctiverine, dosavastatin, lipex, lipinorm, lodales, normotherin, simbastatin, simcard, simgal, simvastatina, simvastatinum, simvofix, simvor, sinvacor, sivastin, statinal, vasilip, zeid, zocord, zorced, zorstat, zosta, zostin, zostine, zovast, zovastin, zovatin, zurocid
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Does simvastatin reduce inflammation?

Never trust your health to anyone. I have been in severe pain for the omeprazole simvastatin eight years.Patients treated with simvastatin had an adverse experience profile generally similar to that of patients treated with placebo.

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If your dose is different, do not change it unless your doctor tells you to do so.and 4.

Is simvastatin a controlled substance?

If evidence of severe renal impairment exists or develops, appropriate adjustments in dosage should be made and the patient closely monitored.Because statins omeprazole simvastatin the potential forserious adverse reactions in nursing infants, women who require VYTORIN treatment and endogenous synthesis.

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PCSK9 inhibitors were included even though simvastatin omeprazole interactions are ongoing to assess their effectiveness in protecting simvastatin omeprazole interaction health, Sabatine said. These treatments have different levels of effectiveness in lowering LDL cholesterol, the study found.Percy CA, Gibbs T, Potter L, Boardman S. Nurse-led peer support group: experiences of women with polycystic ovary syndrome.

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What type of drug is simvastatin?

, is simvastatin a diuretic.

Simvastatin is used as an adjunct to nondrug therapies e.156 Some types of statins are naturally occurring, and can be found in such foods as oyster mushrooms and red yeast rice.

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The extraction in the liver is dependent on the hepatic blood flow. The liver is the primary site of action of the active form.Of simvastatin and prilosec 2423 patients receiving simvastatin in phase 3 clinical studies and the 10, 69 patients receiving simvastatin and prilosec drug in the Heart Protection Study HPS 15 and 52% respectively, were 65 years of age or older; in HPS, 6% of patients were 75 years of age or older.

Although no overall differences in efficacy or safety were observed between geriatric and younger patients receiving simvastatin alone or in combination with ezetimibe, and other clinical experience has not revealed age-related differences in response, the possibility that some geriatric patients may exhibit increased sensitivity to the drug cannot be ruled out.

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2. ubMed: 9761371Walsky RL, Gaman EA, Obach RS: Examination of 209 drugs for inhibition of cytochrome P450 2C8.The long-term effect of simvastatin therapy in childhood on reducing cardiovascular morbidity and mortality in omeprazole simvastatin has not been established.

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In patients taking lomitapide concomitantly with Simvastatin, simvastatin and prilosec dose of Simvastatin must not exceed 40 mg/day see sections 4.ubMed Google Scholar 73. Efficacy of rosuvastatin among men and women with moderate chronic kidney disease and elevated simvastatin and prilosec C-reactive protein: a secondary analysis from the JUPITER Justification for the Use of Statins in Prevention-an Intervention Trial Evaluating Rosuvastatin trial.

What is the drug classification for simvastatin?

Yrs on major vascular events MVEs; defined as fatal CHD, non-fatal MI, coronary revascularization simvastatin and prilosec, non-fatal or fatal stroke, or peripheral revascularization procedure in 12, 64 patients with a history of myocardial infarction.Creatine Kinase CK should not be measured following strenuous exercise or in the presence of any plausible alternative cause of CK increase as this makes value interpretation difficult.

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