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Clinical data | |
---|---|
Trade names | Femara, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a698004 |
License data | US FDA: Letrozole |
Pregnancy category | US: D (Evidence of risk) |
Routes of administration | By mouth (tablets) |
Drug class | Aromatase inhibitor; Antiestrogen |
ATC code | L02BG04 ( WHO ) |
Legal status | |
Legal status | CA : Schedule VII UK: POM (Prescription only) US: ℞-only |
Pharmacokinetic data | |
Bioavailability | 99.9% |
Protein binding | 60%, mainly to albumin |
Metabolism | pharmacologically-inactive carbinol metabolite (4,4΄-methanol-bisbenzonitrile) [1] |
Elimination half-life | 2 days [1] |
Excretion | Kidneys [1] |
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