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Primidone
Clinical data
Trade namesLepsiral, Mysoline, Resimatil, Primaclone
AHFS/Drugs.comMonograph
Pregnancy categoryUS: D (Evidence of risk)
Dependence liabilityModerate-high [ medical citation needed ]
Routes of administrationOral
ATC codeN03AA03 ( WHO )
Legal status
Legal statusUK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability~100% [1]
Protein binding25% [1]
MetabolismHepatic
Elimination half-lifePrimidone: 5-18 h, Phenobarbital: 75-120 h, [1] PEMA: 16 h [2] Time to reach steady state: Primidone: 2-3 days, Phenobarbital&PEMA 1-4weeks [3]
ExcretionRenal

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Mysoline properties
Pills name Mysoline
Active substancesprimidone
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In case of overdose, get medical help or contact a Poison Control Center immediately. Side effects of primidone mysoline 250 mg tablet price OD include: cardiac damage, death, depression, low blood pressure hypotension nausea/vomiting, nervousness, paralysis, respiratory failure, seizures, shortness of breath, slow heart rate, or spasms.Like other antiepileptic drugs, Primidone tablets may cause suicidal thoughts or actions in a very small number of people, about 1 in 500.

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