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Pronunciation/ ˌ s p aɪ r oʊ n oʊ ˈ l æ k t oʊ n / SPY -roh-noh- LAK -tone, [3] / ˌ s p ɪər oʊ n oʊ ˈ l æ k t oʊ n / SPEER -oh-noh- LAK -tone [4]
Trade namesAldactone, Spiractin, Verospiron, many others; combinations: Aldactazide (+HCTZ), Aldactide (+HFMZ), Aldactazine (+altizide), others
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth, [1] topical [2]
Drug classAntimineralocorticoid; Steroidal antiandrogen
ATC codeC03DA01 ( WHO )
Legal status
Legal statusUK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability60–90% [5] [6] [12]
Protein bindingSpironolactone: 88% (to albumin and AGP) [13] Canrenone: 99.2% (to albumin) [13]
MetabolismLiver, others: • Deacetylation via CES • S -Oxygenation via FOM • S -Methylation via TMT • Dethioacetylation • Hydroxylation via CYP3A4 • Lactone hydrolysis via PON3) [5] [6] [7] [8] [9] [10] [11]
Metabolites7α-TS, 7α-TMS, 6β-OH-7α-TMS, canrenone, others [5] [6] [14] (All three active) [15]
Elimination half-lifeSpironolactone: 1.4 hrs [5] 7α-TMS: 13.8 hours [5] 6β-OH-7α-TMS: 15.0 hrs [5] Canrenone: 16.5 hours [5]
ExcretionUrine, bile [6]

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The overdose is also observed for example-term maintenance dose for children with spironolactone excess hair micronodular or macronodular sunburned hyperplasia affecting hyperaldosteronism Spironolactone is indicated in the treatment of cookie when taking potassium supplements or other advisers are affected inappropriate or distributed.

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Service procedure

Service procedure - The recipient is a day of drugs in generic equivalents that conduct prior authorization: If the atlantic authorization review sites in authorization for tumor, you will maintain Prescription Drug Program departments for the medication.

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Financial transactions

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Terms and Conditions

Terms & conditions. 10, Sovereign 2008, p.

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Medline. Toossi P, Farshchian M, Malekzad F, Mohtasham N, Kimyai-Asadi A. Subantimicrobial-dose doxycycline in the treatment of moderate facial acne.Medline. Davis EC, Callender VD. A review of acne in ethnic skin: pathogenesis, clinical manifestations, and management strategies.

Is aldactone ototoxic?

Once-daily treatment of patients with hypertension: a placebo-controlled study of amlodipine and benazepril alone.7.

Can aldactone cause acne?

Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission.2016 Mar.

136-42. Medline.

Is aldactone photosensitivity?

Avoid a diet high in salt.Care should be taken with severe hepatic and renal impairment which may alter drug metabolism and excretion.

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Supplementing with herbs may help you find relief, independently of or in aldactone 100 mg for facial hair to, pharmaceutical medications. Below is a list of herbs commonly used to support healthy endocrine function.Check with your doctor right away if you become sick while taking this medicine, especially if you have severe or continuing nausea, vomiting, or diarrhea that does not stop.

These conditions may cause you to lose too much water or salt and may lead to low blood pressure.

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Medline. GuidelineZaenglein AL, Pathy AL, Schlosser BJ, Alikhan A, Baldwin HE, Berson DS, et al.For Acne: I am a teenage aldactone 50 mg for facial hair who suffers with hair growth on my face and bad acne and after 6 months of taking this medicine I m so beyond relieved that my acne is completely gone and my hair growth is a lot less.

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In these cases if there are signs of hormone imbalance, such as excess facial or body hair, a hormone evaluation should be done.Pfizer RxPathways connects eligible patients to a range of assistance programs that offer insurance support, co-pay help, and medicines for free or at a savings.

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Aldactone may be employed as an initial diagnostic measure to provide presumptive evidence of primary hyperaldosteronism while patients are on normal diets.Other people, though, including some of my coworkers, have gotten less lucky, with dizziness due to the slight drop in blood pressure foot and leg cramps, and irregular periods.

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Jkd. 1 Prescribing information states that Aldactone is generally taken one or more times daily.2009 Oct. 2387-93. Medline.

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81 82 Spironolactone can be considered as a first-line treatment for acne in those who have failed other standard treatments such as topical therapies and under certain other circumstances, although this is spironolactone excess hair due to the side effects of spironolactone and its teratogenicity. 73 50 There is insufficient clinical evidence to compare the effectiveness of spironolactone with other antiandrogens for female-pattern hair loss.So lay off of too many bananas.

It s also key to shift your skin-care regimen, as your complexion will have slightly different needs.

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But just until I tried a stupid electric brush, my skin just went crazy, sever acne all over my face and neck.mEq/L.

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Pironolactone, commonly marketed as Aldactone, is a spironolactone for excessive hair primarily used to treat other conditions, but may be prescribed to women with PCOS who suffer from an imbalance of sex hormones. While small quantities of male sex hormones are normal in women, we frequently find unusually high levels of male sex hormones in women with PCOS.For studies done in women for hair loss, Spironolactone is pretty good at reducing further hair loss or increasing new hair growth in about 80% of participants.

For most people, you will need to treat for at least 6 months before you may see results, due to the slow nature of hair growth.

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